Gene name:
MAST1 (KIAA0973;SAST) ;
Protein name:
Microtubule-associated serine/threonine-protein kinase 1 ;
Alternative:
Syntrophin-associated serine/threonine-protein kinase ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Part of a low affinity complex that associates with, but is distinct from, the post-synaptic density. Interacts with SNTB2.
Function:
Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins.
Subcellular Location:
Cell membrane
Peripheral membrane protein
Cytoplasmic side
Cytoplasm
cytoskeleton
Colocalizes with syntrophins at the cell membrane.
Protein Attributes:
50:
MSDSLWTALS | NFSMPSFPGG | SMFRRTKSCR | TSNRKSLILT | STSPTLPRPH |
100:
SPLPGHLGSS | PLDSPRNFSP | NTPAHFSFAS | SRRADGRRWS | LASLPSSGYG |
150:
TNTPSSTVSS | SCSSQERLHQ | LPYQPTVDEL | HFLSKHFGST | ESITDEDGGR |
200:
RSPAVRPRSR | SLSPGRSPSS | YDNEIVMMNH | VYKERFPKAT | AQMEEKLRDF |
250:
TRAYEPDSVL | PLADGVLSFI | HHQIIELARD | CLTKSRDGLI | TTVYFYELQE |
300:
NLEKLLQDAY | ERSESLEVAF | VTQLVKKLLI | IISRPARLLE | CLEFNPEEFY |
350:
HLLEAAEGHA | KEGHLVKTDI | PRYIIRQLGL | TRDPFPDVVH | LEEQDSGGSN |
400:
TPEQDDLSEG | RSSKAKKPPG | ENDFDTIKLI | SNGAYGAVYL | VRHRDTRQRF |
450:
AMKKINKQNL | ILRNQIQQAF | VERDILTFAE | NPFVVGMFCS | FETRRHLCMV |
500:
MEYVEGGDCA | TLLKNIGALP | VEMARMYFAE | TVLALEYLHN | YGIVHRDLKP |
550:
DNLLITSMGH | IKLTDFGLSK | MGLMSLTTNL | YEGHIEKDAR | EFLDKQVCGT |
600:
PEYIAPEVIL | RQGYGKPVDW | WAMGIILYEF | LVGCVPFFGD | TPEELFGQVI |
650:
SDDILWPEGD | EALPTEAQLL | ISSLLQTNPL | VRLGAGGAFE | VKQHSFFRDL |
700:
DWTGLLRQKA | EFIPHLESED | DTSYFDTRSD | RYHHVNSYDE | DDTTEEEPVE |
750:
IRQFSSCSPR | FSKVYSSMEQ | LSQHEPKTPV | AAAGSSKREP | STKGPEEKVA |
800:
GKREGLGGLT | LREKTWRGGS | PEIKRFSASE | ASFLEGEASP | PLGARRRFSA |
850:
LLEPSRFSAP | QEDEDEARLR | RPPRPSSDPA | GSLDARAPKE | ETQGEGTSSA |
900:
GDSEATDRPR | PGDLCPPSKD | GDASGPRATN | DLVLRRARHQ | QMSGDVAVEK |
950:
RPSRTGGKVI | KSASATALSV | MIPAVDPHGS | SPLASPMSPR | SLSSNPSSRD |
1000:
SSPSRDYSPA | VSGLRSPITI | QRSGKKYGFT | LRAIRVYMGD | TDVYSVHHIV |
1050:
WHVEEGGPAQ | EAGLCAGDLI | THVNGEPVHG | MVHPEVVELI | LKSGNKVAVT |
1100:
TTPFENTSIR | IGPARRSSYK | AKMARRNKRP | SAKEGQESKK | RSSLFRKITK |
1150:
QSNLLHTSRS | LSSLNRSLSS | SDSLPGSPTH | GLPARSPTHS | YRSTPDSAYL |
1200:
GASSQSSSPA | SSTPNSPASS | ASHHIRPSTL | HGLSPKLHRQ | YRSARCKSAG |
1250:
NIPLSPLAHT | PSPTQASPPP | LPGHTVGSSH | TTQSFPAKLH | SSPPVVRPRP |
1300:
KSAEPPRSPL | LKRVQSAEKL | GASLSADKKG | ALRKHSLEVG | HPDFRKDFHG |
1350:
ELALHSLAES | DGETPPVEGL | GAPRQVAVRR | LGRQESPLSL | GADPLLPEGA |
1400:
SRPPVSSKEK | ESPGGAEACT | PPRATTPGGR | TLERDVGCTR | HQSVQTEDGT |
1450:
GGMARAVAKA | ALSPVQEHET | GRRSSSGEAG | TPLVPIVVEP | ARPGAKAVVP |
1500:
QPLGADSKGL | QEPAPLAPSV | PEAPRGRERW | VLEVVEERTT | LSGPRSKPAS |
1550:
PKLSPEPQTP | SLAPAKCSAP | SSAVTPVPPA | SLLGSGTKPQ | VGLTSRCPAE |
1570:
AVPPAGLTKK | GVSSPAPPGP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Human Microtubule-associated serine/threonine-protein kinase 1
ELISA Kit for Human Microtubule-associated serine/threonine-protein kinase 1
ELISA Kit for Human Microtubule-associated serine/threonine-protein kinase 1
CLIA Kit for Human Microtubule-associated serine/threonine-protein kinase 1
CLIA Kit for Human Microtubule-associated serine/threonine-protein kinase 1
CLIA Kit for Human Microtubule-associated serine/threonine-protein kinase 1
Polyclonal Antibody for Human Microtubule-associated serine/threonine-protein kinase 1
Polyclonal Antibody for Human Microtubule-associated serine/threonine-protein kinase 1
Polyclonal Antibody for Human Microtubule-associated serine/threonine-protein kinase 1
Monoclonal Antibody for Human Microtubule-associated serine/threonine-protein kinase 1
Monoclonal Antibody for Human Microtubule-associated serine/threonine-protein kinase 1
Monoclonal Antibody for Human Microtubule-associated serine/threonine-protein kinase 1
Protein for Human Microtubule-associated serine/threonine-protein kinase 1
Protein for Human Microtubule-associated serine/threonine-protein kinase 1
Protein for Human Microtubule-associated serine/threonine-protein kinase 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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Cited for : VARIANTS [LARGE SCALE ANALYSIS] THR-269; TYR-1240 AND SER-1292